Which statement most accurately describes the hypothalamic-pituitary-adrenal axis of the stress response? 1) The hypothalamic-pituitary-adrenal axis is responsible for the release of cortisol in response to stress. 2) The hypothalamic-pituitary-adrenal axis is responsible for the release of adrenaline in response to stress. 3) The hypothalamic-pituitary-adrenal axis is responsible for the release of oxytocin in response to stress. 4) The hypothalamic-pituitary-adrenal axis is responsible for the release of insulin in response to stress.