A mutation in a person changed the insulin gene to read TCT instead of the normal
TGA. Using your codon chart, look up the amino acid that is coded for by both the
normal and the mutant DNA. Will this person be diabetic, assuming this is the only
mutation in the gene?

A mutation in a person changed the insulin gene to read TCT instead of the normal TGA Using your codon chart look up the amino acid that is coded for by both th class=

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Answer:

Yes, the person will be diabetic because the mutation alters the amino acid sequence.

Explanation:

  • The normal template DNA sequence is TCT and its corresponding mRNA is AGA which codes for the amino acid arginine.
  • The mutant DNA sequence is TGA, its corresponding mRNA is ACU which codes for the amino acid threonine.
  • Therefore, since the amino acid sequence is altered, the protein will be abnormal and non-functional.