The immunological targeting of cancer cells by this oncoprotein to grow and disseminate throughout the body is confirmed by the biochemical and functional characterization of mutant KRAS epitopes.
KRAS mutations are among the most prevalent gene mutations associated with cancer, found in around 25% of malignancies. They frequently contribute to pancreatic, colorectal, and lung malignancies. KRAS is the cause of 85% - 90% of pancreatic cancer cases, 40% of colorectal malignancies, and 32% of lung cancer cases.
The KRAS gene is a member of the oncogene gene family. Oncogenes can transform healthy cells into malignant ones when they are altered. The HRAS and NRAS genes are two more members of the Ras group of oncogenes, which also contain the KRAS gene.
Learn more about the epitopes at
https://brainly.com/question/9539970?referrer=searchResults
#SPJ4
